Anti-EFNB2 Antibody

Rs. 68,577.00
SKU stj72325

General Information

Product name Anti-EFNB2 Antibody
Short Description Goat polyclonal to EFNB2
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-EFNB2 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 36.9 kDa
Database Links
Alternative Names EFNB2Ephrin-B2 antibodyEPH-related receptor tyrosine kinase ligand 5 antibodyLERK-5 antibodyHTK ligand antibodyHTK-LEFNB2 antibodyEPLG5 antibodyHTKL antibodyLERK5
Function Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development, Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells, The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling, Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4, Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration, EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells, May play a role in constraining the orientation of longitudinally projecting axons,
Cellular Localization Membrane
Tissue Specificity Lung and kidney
Swiss-Prot Key

 

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