Anti-EIF2S2 Antibody

Rs. 45,619.00
SKU stj28167

General Information

Product name Anti-EIF2S2 Antibody
Short Description Rabbit polyclonal to EIF2S2
Description Eukaryotic translation initiation factor 2 (EIF-2) functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA and binding to a 40S ribosomal subunit. EIF-2 is composed of three subunits, alpha, beta, and gamma, with the protein encoded by this gene representing the beta subunit. The beta subunit catalyzes the exchange of GDP for GTP, which recycles the EIF-2 complex for another round of initiation. Multiple transcript variants encoding different isoforms have been found for this gene.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-EIF2S2 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 134-333 of human EIF2S2 (NP_003899.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 38.4 kDa
Database Links
Alternative Names EIF2S2Eukaryotic translation initiation factor 2 subunit 2 antibodyEukaryotic translation initiation factor 2 subunit beta antibodyeIF-2-betaEIF2S2 antibodyEIF2B
Function eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA, This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex, Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex, In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B
Cellular Localization
Tissue Specificity
Swiss-Prot Key

 

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