Anti-ELAVL3 Antibody

Rs. 45,619.00
SKU stj29931

General Information

Product name Anti-ELAVL3 Antibody
Short Description Rabbit polyclonal to ELAVL3
Description A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Applications WB,IHC
Dilution range WB 1:500 - 1:1000
IHC 1:50 - 1:200
Protein Name Anti-ELAVL3 Antibody
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ELAVL3 (NP_001411.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 39.5 kDa
Database Links
Alternative Names ELAVL3ELAV-like protein 3 antibodyHu-antigen C antibodyHuC antibodyParaneoplastic cerebellar degeneration-associated antigen antibodyParaneoplastic limbic encephalitis antigen 21ELAVL3 antibodyHUC antibodyPLE21
Function Binds to AU-rich sequences (AREs) of target mRNAs, including VEGF mRNA, May also bind poly-A tracts via RRM 3 (By similarity), May be involved in neuronal differentiation and maintenance.
Cellular Localization
Tissue Specificity Brain specific
Swiss-Prot Key

 

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