Anti-ELF3 Antibody

Rs. 68,577.00
SKU stj70201

General Information

Product name Anti-ELF3 Antibody
Short Description Goat polyclonal to ELF3
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-ELF3 Antibody
Immunogen C Terminus
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 41.5 kDa
Database Links
Alternative Names ELF3ETS-related transcription factor Elf-3 antibodyE74-like factor 3 antibodyEpithelial-restricted with serine box antibodyEpithelium-restricted Ets protein ESX antibodyEpithelium-specific Ets transcription factor 1 antibodyESE-1ELF3 antibodyERT antibodyESX antibodyJEN
Function Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT], Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter, Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters, Represses KRT4 promoter activity, Involved in mediating vascular inflammation, May play an important role in epithelial cell differentiation and tumorigenesis, May be a critical downstream effector of the ERBB2 signaling pathway, May be associated with mammary gland development and involution, Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity),
Cellular Localization Cytoplasm
Tissue Specificity Expressed exclusively in tissues containing a high content of terminally differentiated epithelial cells including mammary gland, colon, trachea, kidney, prostate, uterus, stomach and skin,
Swiss-Prot Key

 

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