Anti-ELL2 antibody

Rs. 50,211.00
SKU stj92896

General Information

Product name Anti-ELL2 antibody
Short Description
Description Rabbit polyclonal to ELL2.
Applications IHC,ELISA
Dilution range IHC 1:100-1:300ELISA 1:20000
Protein Name Anti-ELL2 antibody
Immunogen Synthesized peptide derived from human ELL2
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 72.354 kDa
Database Links
Alternative Names RNA polymerase II elongation factor ELL2 antibody
Function Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III . Plays a role in immunoglobulin secretion in plasma cells: directs efficient alternative mRNA processing, influencing both proximal poly(A) site choice and exon skipping, as well as immunoglobulin heavy chain (IgH) alternative processing. Probably acts by regulating histone modifications accompanying transition from membrane-specific to secretory IgH mRNA expression.
Cellular Localization Nucleus.
Tissue Specificity
Swiss-Prot Key

 

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