Anti-EMR2 antibody

Rs. 50,211.00
SKU stj92911

General Information

Product name Anti-EMR2 antibody
Short Description
Description Rabbit polyclonal to EMR2.
Applications WB,IF,ELISA
Dilution range WB 1:500-1:2000IF 1:200-1:1000ELISA 1:20000
Protein Name Anti-EMR2 antibody
Immunogen Synthesized peptide derived from human EMR2
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 85 kDa
Database Links
Alternative Names Adhesion G protein-coupled receptor E2 antibody
EGF-like module receptor 2 antibody
EGF-like module-containing mucin-like hormone receptor-like 2 antibody
CD antigen CD312 antibody
Function Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through G-proteins. Is a regulator of mast cell degranulation .
Cellular Localization Cell membrane
Tissue Specificity Expression is restricted to myeloid cells. Highest expression was found in peripheral blood leukocytes, followed by spleen and lymph nodes, with intermediate to low levels in thymus, bone marrow, fetal liver, placenta, and lung, and no expression in heart, brain, skeletal muscle, kidney, or pancreas. Expression is also detected in monocyte/macrophage and Jurkat cell lines but not in other cell lines tested. High expression in mast cells .
Swiss-Prot Key

 

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