| Gene ID |
|
| Gene Symbol |
|
| Molecular Weight |
34.9 kDa |
| Database Links |
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| Alternative Names |
EPCAMEpithelial cell adhesion molecule antibodyEp-CAM antibodyAdenocarcinoma-associated antigen antibodyCell surface glycoprotein Trop-1 antibodyEpithelial cell surface antigen antibodyEpithelial glycoprotein antibodyEGP antibodyEpithelial glycoprotein 314 antibodyEGP314 antibodyhEGP314 antibodyKS 1/4 antigen antibodyKSA antibodyMajor gastrointestinal tumor-associated protein GA733-2 antibodyTumor-associated calcium signal transducer 1 antibodyCD antigen CD326EPCAM antibodyGA733-2 antibodyM1S2 antibodyM4S1 antibodyMIC18 antibodyTACSTD1 antibodyTROP1 |
| Function |
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection, Plays a role in embryonic stem cells proliferation and differentiation, Up-regulates the expression of FABP5, MYC and cyclins A and E, |
| Cellular Localization |
Lateral cell membrane |
| Tissue Specificity |
Highly and selectively expressed by undifferentiated rather than differentiated embryonic stem cells (esc), levels rapidly diminish as soon as esc's differentiate (at protein levels), expressed in almost all epithelial cell membranes but not on mesodermal or neural cell membranes, found on the surface of adenocarcinoma, |
| Swiss-Prot Key |
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