Anti-Ephrin-A3 antibody

Rs. 50,211.00
SKU stj92956

General Information

Product name Anti-Ephrin-A3 antibody
Short Description Rabbit polyclonal to Ephrin-A3.
Description Ephrin-A3 is a protein encoded by the EFNA3 gene which is approximately 26,3 kDa. Ephrin-A3 is localised to the cell membrane. It is involved in EPHA forward signalling, the Ras signalling pathway, developmental biology and axon guidance. The ephrins make up the largest subfamily of receptor protein-tyrosine kinases, they are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Ephrin-A3 is expressed in brain, skeletal muscle, thymus, prostate, testis, ovary, and peripheral blood leukocytes. Mutations in the EFNA3 gene may result in Androgenic Alopecia. stj92956 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Ephrin-A3 protein.
Applications WB,IHC,IF,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000
Protein Name Anti-Ephrin-A3 antibody
Immunogen Synthesized peptide derived from human Ephrin-A3
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 38 kDa
Database Links
Alternative Names Ephrin-A3 antibody
EFL-2 antibody
EHK1 ligand antibody
EHK1-L antibody
EPH-related receptor tyrosine kinase ligand 3 antibody
LERK-3 antibody
EFL2 antibody
EPLG3 antibody
LERK3 antibody
Function Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling .
Cellular Localization Cell membrane. Lipid-anchor, GPI-anchor.
Tissue Specificity Expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes.
Swiss-Prot Key

 

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