Anti-ERAB antibody

Rs. 50,211.00
SKU stj92970

General Information

Product name Anti-ERAB antibody
Short Description
Description Rabbit polyclonal to ERAB.
Applications WB,IHC,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000
Protein Name Anti-ERAB antibody
Immunogen Synthesized peptide derived from human ERAB
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse,Rat,Monkey
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 27 kDa
Database Links
Alternative Names 3-hydroxyacyl-CoA dehydrogenase type-2 antibody
17-beta-hydroxysteroid dehydrogenase 10 antibody
17-beta-HSD 10 antibody
2-methyl-3-hydroxybutyryl-CoA dehydrogenase antibody
MHBD antibody
3-hydroxy-2-methylbutyryl-CoA dehydrogenase antibody
3-hydroxyacyl-CoA dehydrogenase type II antibody
Endoplasmic reticulum-associated amyloid beta-peptide-binding protein antibody
Mitochondrial ribonuclease P protein 2 antibody
Mitochondrial RNase P protein 2 antibody
Short chain dehydrogenase/reductase family 5C member 1 antibody
Short-chain type dehydrogenase/reductase XH98G2 antibody
Type II HADH antibody
HADH2 antibody
MRPP2 antibody
SCHAD antibody
SDR5C1 antibody
XH98G2 antibody
Function Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
Cellular Localization Mitochondrion
Tissue Specificity Ubiquitously expressed in normal tissues but is overexpressed in neurons affected in AD.
Swiss-Prot Key

 

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