Anti-ERAL1 Antibody

Rs. 61,689.00
SKU stj27770

General Information

Product name Anti-ERAL1 Antibody
Short Description Rabbit polyclonal to ERAL1
Description The protein encoded by this gene is a GTPase that localizes to the mitochondrion. The encoded protein binds to the 3' terminal stem loop of 12S mitochondrial rRNA and is required for proper assembly of the 28S small mitochondrial ribosomal subunit. Deletion of this gene has been shown to cause mitochondrial dysfunction, growth retardation, and apoptosis. Several transcript variants encoding different isoforms have been found for this gene.
Applications WB
Dilution range WB 1:1000 - 1:2000
Protein Name Anti-ERAL1 Antibody
Immunogen A synthetic peptide of human ERAL1
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 48.4 kDa
Database Links
Alternative Names ERAL1GTPase Era antibodymitochondrial antibodyH-ERA antibodyhERA antibodyConserved ERA-like GTPase antibodyCEGA antibodyERA-W antibodyERA-like protein 1ERAL1 antibodyHERA
Function Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly, Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region, May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly.
Cellular Localization Mitochondrion matrix, Mitochondrion inner membrane
Tissue Specificity
Swiss-Prot Key

 

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