Anti-ErbB-3 antibody

Rs. 50,211.00
SKU stj92975

General Information

Product name Anti-ErbB-3 antibody
Short Description
Description Rabbit polyclonal to ErbB-3.
Applications WB,IHC,IF,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000
Protein Name Anti-ErbB-3 antibody
Immunogen Synthesized peptide derived from human ErbB-3 around the non-phosphorylation site of Y1222.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 148 kDa
Database Links
Alternative Names Receptor tyrosine-protein kinase erbB-3 antibody
Proto-oncogene-like protein c-ErbB-3 antibody
Tyrosine kinase-type cell surface receptor HER3 antibody
HER3 antibody
Function Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase . May also be activated by CSPG5 .
Cellular Localization Isoform 1: Cell membrane. Single-pass type I membrane protein.. Isoform 2: Secreted.
Tissue Specificity Epithelial tissues and brain.
Swiss-Prot Key

 

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