Anti-ERCC1 antibody

Rs. 50,211.00
SKU stj92979

General Information

Product name Anti-ERCC1 antibody
Short Description
Description Rabbit polyclonal to ERCC1.
Applications WB,IHC,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300ELISA 1:20000
Protein Name Anti-ERCC1 antibody
Immunogen Synthesized peptide derived from human ERCC1
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 36 kDa
Database Links
Alternative Names DNA excision repair protein ERCC-1 antibody
Function Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.
Cellular Localization Isoform 1: Nucleus.. Isoform 2: Cytoplasm. Nucleus.. Isoform 3: Nucleus.. Isoform 4: Nucleus.
Tissue Specificity
Swiss-Prot Key

 

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