Anti-ERK 3 antibody

Rs. 50,211.00
SKU stj92993

General Information

Product name Anti-ERK 3 antibody
Short Description
Description Rabbit polyclonal to ERK 3.
Applications WB,IHC,IF,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000
Protein Name Anti-ERK 3 antibody
Immunogen Synthesized peptide derived from human ERK 3
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 85 kDa
Database Links
Alternative Names Mitogen-activated protein kinase 6 antibody
MAP kinase 6 antibody
MAPK 6 antibody
Extracellular signal-regulated kinase 3 antibody
ERK-3 antibody
MAP kinase isoform p97 antibody
p97-MAPK antibody
ERK3 antibody
PRKM6 antibody
Function Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle .
Cellular Localization Cytoplasm Nucleus. Translocates to the cytoplasm following interaction with MAPKAPK5.
Tissue Specificity Highest expression in the skeletal muscle, followed by the brain. Also found in heart, placenta, lung, liver, pancreas, kidney and skin fibroblasts.
Swiss-Prot Key

 

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