Anti-Ezrin antibody

Rs. 50,211.00
SKU stj93015

General Information

Product name Anti-Ezrin antibody
Short Description
Description Rabbit polyclonal to Ezrin.
Applications WB,ELISA
Dilution range WB 1:500-1:2000ELISA 1:40000
Protein Name Anti-Ezrin antibody
Immunogen Synthesized peptide derived from human Ezrin around the non-phosphorylation site of Y478.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 80 kDa
Database Links
Alternative Names Ezrin antibody
Cytovillin antibody
Villin-2 antibody
p81 antibody
VIL2 antibody
Function Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.
Cellular Localization Apical cell membrane Cell projection Cell projection, microvillus membrane Cell projection, ruffle membrane Cytoplasm, cell cortex Cytoplasm, cytoskeleton. Localization to the apical membrane of parietal cells depends on the interaction with MPP5. Localizes to cell extensions and peripheral processes of astrocytes . Microvillar peripheral membrane protein (cytoplasmic side).
Tissue Specificity Expressed in cerebral cortex, basal ganglia, hippocampus, hypophysis, and optic nerve. Weakly expressed in brain stem and diencephalon. Stronger expression was detected in gray matter of frontal lobe compared to white matter (at protein level). Component of the microvilli of intestinal epithelial cells. Preferentially expressed in astrocytes of hippocampus, frontal cortex, thalamus, parahippocampal cortex, amygdala, insula, and corpus callosum. Not detected in neurons in most tissues studied.
Swiss-Prot Key

 

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