Anti-FABP2 Antibody

Rs. 45,619.00
SKU stj23603

General Information

Product name Anti-FABP2 Antibody
Short Description Rabbit polyclonal to FABP2
Description The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family with nearly twenty identified members. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Intestinal fatty acid-binding protein 2 gene contains four exons and is an abundant cytosolic protein in small intestine epithelial cells. This gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:10 - 1:100
Protein Name Anti-FABP2 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-132 of human FABP2 (NP_000125.2).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 15.2 kDa
Database Links
Alternative Names FABP2Fatty acid-binding protein antibodyintestinal antibodyFatty acid-binding protein 2 antibodyIntestinal-type fatty acid-binding protein antibodyI-FABPFABP2 antibodyFABPI
Function FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters, FABP2 is probably involved in triglyceride-rich lipoprotein synthesis, Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids, FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor
Cellular Localization Cytoplasm
Tissue Specificity Expressed in the small intestine and at much lower levels in the large intestine, highest expression levels in the jejunum.
Swiss-Prot Key

 

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