Anti-FABP6 Antibody

Rs. 45,619.00
SKU stj28986

General Information

Product name Anti-FABP6 Antibody
Short Description Rabbit polyclonal to FABP6
Description This gene encodes the ileal fatty acid binding protein. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. Transcript variants generated by alternate transcription promoters and/or alternate splicing have been found for this gene.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-FABP6 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human FABP6 (NP_001436.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 14.4 kDa
Database Links
Alternative Names FABP6Gastrotropin antibodyGT antibodyFatty acid-binding protein 6 antibodyIleal lipid-binding protein antibodyILBP antibodyIntestinal 15 kDa protein antibodyI-15P antibodyIntestinal bile acid-binding protein antibodyI-BABPFABP6 antibodyILBP antibodyILLBP
Function Binds to bile acids and is involved in enterohepatic bile acid metabolism, Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (By similarity), In vitro binds to bile acids in the order: deoxycholic acid > cholic acid > chenodeoxycholic acid and respective BA conjugation modifies affinities in the order taurine-conjugated > glycine-conjugated > unconjugated bile acids, Stimulates gastric acid and pepsinogen secretion (By similarity).
Cellular Localization Cytoplasm
Tissue Specificity Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine, isoform 2 is xpressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum, isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level).
Swiss-Prot Key

 

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