Anti-FANCG Antibody

Rs. 45,619.00
SKU stj27962

General Information

Product name Anti-FANCG Antibody
Short Description Rabbit polyclonal to FANCG
Description The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-FANCG Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 343-622 of human FANCG (NP_004620.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 68.6 kDa
Database Links
Alternative Names FANCGFanconi anemia group G protein antibodyProtein FACG antibodyDNA repair protein XRCC9FANCG antibodyXRCC9
Function DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function, May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability, Candidate tumor suppressor gene
Cellular Localization Nucleus.
Tissue Specificity Highly expressed in testis and thymus, found in lymphoblasts
Swiss-Prot Key

 

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