Anti-FCGR2B Antibody

Rs. 68,577.00
SKU stj70681

General Information

Product name Anti-FCGR2B Antibody
Short Description Goat polyclonal to FCGR2B
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-FCGR2B Antibody
Immunogen C Terminus
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 34 kDa
Database Links
Alternative Names FCGR2BLow affinity immunoglobulin gamma Fc region receptor II-b antibodyIgG Fc receptor II-b antibodyCDw32 antibodyFc-gamma RII-b antibodyFc-gamma-RIIb antibodyFcRII-b antibodyCD antigen CD32FCGR2B antibodyCD32 antibodyFCG2 antibodyIGFR2
Function Receptor for the Fc region of complexed or aggregated immunoglobulins gamma, Low affinity receptor, Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells, Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor, Isoform IIB1 fails to mediate endocytosis or phagocytosis, Isoform IIB2 does not trigger phagocytosis
Cellular Localization Cell membrane
Tissue Specificity Is the most broadly distributed fc-gamma-receptor, expressed in monocyte, neutrophils, macrophages, basophils, eosinophils, langerhans cells, b-cells, platelets cells and placenta (endothelial cells), not detected in natural killer cells
Swiss-Prot Key

 

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