Anti-FAIM3 Antibody

Rs. 45,619.00
SKU stj28242

General Information

Product name Anti-FAIM3 Antibody
Short Description Rabbit polyclonal to FCMR
Description
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-FAIM3 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 18-251 of human FAIM3 (NP_005440.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 43.1 kDa
Database Links
Alternative Names FCMRFas apoptotic inhibitory molecule 3 antibodyIgM Fc fragment receptor antibodyRegulator of Fas-induced apoptosis TosoFCMR antibodyFAIM3 antibodyTOSO
Function May play a role in the immune system processes, Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL, Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream, May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
Cellular Localization Membrane
Tissue Specificity Expressed in lymph nodes, peripheral blood leukocytes, lung, thymus and kidneys, very weak expression detected in spleen, liver, heart, and salivary gland, expressed in lymphoid cell lines such as jurkat, cem-t4, molt-4, hb11
Swiss-Prot Key

 

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