Anti-FGA Antibody

Rs. 68,577.00
SKU stj73374

General Information

Product name Anti-FGA Antibody
Short Description Goat polyclonal to FGA
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-FGA Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 95 kDa
Database Links
Alternative Names FGAFibrinogen alpha chainFGA
Function Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix, Fibrin has a major function in hemostasis as one of the primary components of blood clots, In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization, Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood, However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo, Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway, Maternal fibrinogen is essential for successful pregnancy, Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage, May also facilitate the immune response via both innate and T-cell mediated pathways,
Cellular Localization Secreted
Tissue Specificity Detected in blood plasma (at protein level),
Swiss-Prot Key

 

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