Anti-FGFBP1 Antibody

Rs. 45,619.00
SKU stj29594

General Information

Product name Anti-FGFBP1 Antibody
Short Description Rabbit polyclonal to FGFBP1
Description This gene encodes a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-FGFBP1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 24-234 of human FGFBP1 (NP_005121.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 26.3 kDa
Database Links
Alternative Names FGFBP1Fibroblast growth factor-binding protein 1 antibodyFGF-BP antibodyFGF-BP1 antibodyFGF-binding protein 1 antibodyFGFBP-1 antibody17 kDa heparin-binding growth factor-binding protein antibody17 kDa HBGF-binding protein antibodyHBp17FGFBP1 antibodyFGFBP antibodyHBP17
Function Acts as a carrier protein that release fibroblast-binding factors (FGFs) from the extracellular matrix (EM) storage and thus enhance the mitogenic activity of FGFs, Enhances FGF2 signaling during tissue repair, angiogenesis and in tumor growth.
Cellular Localization Secreted, extracellular space
Tissue Specificity Expressed in the suprabasal region of the epidermis, in hair follicles, the basement membrane at the dermo-epidermal junction (occasionally extending into the basement membrane of dermal blood vessels), wounded skin and several invasive squamous cell carcinomas (at protein level), expressed in normal and wounded skin and various squamous cell carcinomas.
Swiss-Prot Key

 

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