Anti-FKBP8 Antibody

Rs. 57,098.00
SKU stj71583

General Information

Product name Anti-FKBP8 Antibody
Short Description Goat polyclonal to FKBP8
Description
Applications ELISA
Dilution range
Protein Name Anti-FKBP8 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 44.6 kDa
Database Links
Alternative Names FKBP8Peptidyl-prolyl cis-trans isomerase FKBP8 antibodyPPIase FKBP8FKBP8 antibodyFKBP38
Function Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium, Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state, The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets, The active form of FKBP8 may therefore play a role in the regulation of apoptosis,
Cellular Localization Mitochondrion
Tissue Specificity Widely expressed, highest levels seen in the brain, highly abundant in the retina,
Swiss-Prot Key

 

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