Anti-FLNB Antibody

Rs. 57,098.00
SKU stj71037

General Information

Product name Anti-FLNB Antibody
Short Description Goat polyclonal to FLNB
Description
Applications ELISA
Dilution range
Protein Name Anti-FLNB Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 278.2 kDa
Database Links
Alternative Names FLNBFilamin-B antibodyFLN-B antibodyABP-278 antibodyABP-280 homolog antibodyActin-binding-like protein antibodyBeta-filamin antibodyFilamin homolog 1 antibodyFh1 antibodyFilamin-3 antibodyThyroid autoantigen antibodyTruncated actin-binding protein antibodyTruncated ABPFLNB antibodyFLN1L antibodyFLN3 antibodyTABP antibodyTAP
Function Connects cell membrane constituents to the actin cytoskeleton, May promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins, Anchors various transmembrane proteins to the actin cytoskeleton, Interaction with FLNA may allow neuroblast migration from the ventricular zone into the cortical plate, Various interactions and localizations of isoforms affect myotube morphology and myogenesis, Isoform 6 accelerates muscle differentiation in vitro
Cellular Localization Cytoplasm, cell cortex, Cytoplasm, cytoskeleton, Cytoplasm, cytoskeleton, stress fiber, Cytoplasm, myofibril, sarcomere, Z line, Cytoplasm, cytoskeleton,
Tissue Specificity Ubiquitous, isoform 1 and isoform 2 are expressed in placenta, bone marrow, brain, umbilical vein endothelial cells (huvec), retina and skeletal muscle, isoform 1 is predominantly expressed in prostate, uterus, liver, thyroid, stomach, lymph node, small intestine, spleen, skeletal muscle, kidney, placenta, pancreas, heart, lung, platelets, endothelial cells, megakaryocytic and erythroleukemic cell lines, isoform 2 is predominantly expressed in spinal cord, platelet and daudi cells, also expressed in thyroid adenoma, neurofibrillary tangles (nft), senile plaques in the hippocampus and cerebral cortex in alzheimer disease (ad), isoform 3 and isoform 6 are expressed predominantly in lung, heart, skeletal muscle, testis, spleen, thymus and leukocytes, isoform 4 and isoform 5 are expressed in heart,
Swiss-Prot Key

 

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