Anti-FMO1 Antibody

Rs. 45,619.00
SKU stj28988

General Information

Product name Anti-FMO1 Antibody
Short Description Rabbit polyclonal to FMO1
Description Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Several transcript variants encoding different isoforms have been found for this gene.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:100
Protein Name Anti-FMO1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 363-532 of human FMO1 (NP_002012.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 60.3 kDa
Database Links
Alternative Names FMO1Dimethylaniline monooxygenase 1 FMO1
Function This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides, Form I catalyzes the N-oxygenation of secondary and tertiary amines
Cellular Localization Microsome membrane
Tissue Specificity Expressed mainly in fetal and adult liver.
Swiss-Prot Key

 

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