Anti-FMO5 Antibody

Rs. 45,619.00
SKU stj29986

General Information

Product name Anti-FMO5 Antibody
Short Description Rabbit polyclonal to FMO5
Description Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Protein Name Anti-FMO5 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-285 of human FMO5 (NP_001138302.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 60.2 kDa
Database Links
Alternative Names FMO5Dimethylaniline monooxygenase 5 FMO5
Function In contrast with other forms of FMO it does not seem to be a drug-metabolizing enzyme
Cellular Localization Microsome membrane, Endoplasmic reticulum membrane
Tissue Specificity Expressed in fetal and adult liver
Swiss-Prot Key

 

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