Anti-FN3KRP Antibody

Rs. 61,689.00
SKU stj26998

General Information

Product name Anti-FN3KRP Antibody
Short Description Rabbit polyclonal to FN3KRP
Description A high concentration of glucose can result in non-enzymatic oxidation of proteins by reaction of glucose and lysine residues (glycation). Proteins modified in this way are less active or functional. This gene encodes an enzyme which catalyzes the phosphorylation of psicosamines and ribulosamines compared to the neighboring gene which encodes a highly similar enzyme, fructosamine-3-kinase, which has different substrate specificity. The activity of both enzymes may result in deglycation of proteins to restore their function. Alternative splicing results in multiple transcript variants.
Applications WB,IHC
Dilution range WB 1:500 - 1:1000
IHC 1:20 - 1:50
Protein Name Anti-FN3KRP Antibody
Immunogen A synthetic Peptide of human FN3KRP
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 34.4 kDa
Database Links
Alternative Names FN3KRPKetosamine-3-kinase FN3KRP
Function Phosphorylates psicosamines and ribulosamines, but not fructosamines, on the third carbon of the sugar moiety, Protein-bound psicosamine 3-phosphates and ribulosamine 3-phosphates are unstable and decompose under physiological conditions, Thus phosphorylation leads to deglycation.
Cellular Localization
Tissue Specificity Expressed in erythrocytes.
Swiss-Prot Key

 

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