Anti-FNBP1 Antibody

Rs. 68,577.00
SKU stj70595

General Information

Product name Anti-FNBP1 Antibody
Short Description Goat polyclonal to FNBP1
Description
Applications ELISA, WB, IHC
Dilution range
Protein Name Anti-FNBP1 Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 71.3 kDa
Database Links
Alternative Names FNBP1Formin-binding protein 1 antibodyFormin-binding protein 17 antibodyhFBP17FNBP1 antibodyFBP17 antibodyKIAA0554
Function May act as a link between RND2 signaling and regulation of the actin cytoskeleton (By similarity), Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during the late stage of clathrin-mediated endocytosis, Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules, Also enhances actin polymerization via the recruitment of WASL/N-WASP, which in turn activates the Arp2/3 complex, Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles, May be required for the lysosomal retention of FASLG/FASL,
Cellular Localization Cytoplasm, Cytoplasm, cytoskeleton, Cytoplasm, cell cortex, Lysosome, Cytoplasmic vesicle, Cell membrane
Tissue Specificity Very highly expressed in the epithelial cells of the gastrointestinal tract, respiratory, reproductive and urinary systems, also highly expressed in brown adipose tissue, cardiomyocytes, enteric ganglia and glucagon producing cells of the pancreas, expressed in germ cells of the testis and all regions of the brain,
Swiss-Prot Key

 

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