Anti-FOS Antibody

Rs. 68,577.00
SKU stj72884

General Information

Product name Anti-FOS Antibody
Short Description Goat polyclonal to FOS
Description
Applications ELISA, WB, IHC
Dilution range
Protein Name Anti-FOS Antibody
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 40.7 kDa
Database Links
Alternative Names FOSProto-oncogene c-Fos antibodyCellular oncogene fos antibodyG0/G1 switch regulatory protein 7FOS antibodyG0S7
Function Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor, In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites, On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling, Has a critical function in regulating the development of cells destined to form and maintain the skeleton, It is thought to have an important role in signal transduction, cell proliferation and differentiation, In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A, This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum,
Cellular Localization Nucleus, Endoplasmic reticulum, Cytoplasm, cytosol,
Tissue Specificity
Swiss-Prot Key

 

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