Anti-FoxO3A antibody

Rs. 50,211.00
SKU stj93128

General Information

Product name Anti-FoxO3A antibody
Short Description
Description Rabbit polyclonal to FoxO3A.
Applications WB,IHC,IF,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000
Protein Name Anti-FoxO3A antibody
Immunogen Synthesized peptide derived from human FoxO3A around the non-phosphorylation site of S253.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 97/71 kDa
Database Links
Alternative Names Forkhead box protein O3 antibody
AF6q21 protein antibody
Forkhead in rhabdomyosarcoma-like 1 antibody
FKHRL1 antibodyA antibody
Function Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.
Cellular Localization Cytoplasm, cytosol Nucleus. Retention in the cytoplasm contributes to its inactivation. Translocates to the nucleus upon oxidative stress and in the absence of survival factors.
Tissue Specificity Ubiquitous.
Swiss-Prot Key

 

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