Anti-FRK Antibody

Rs. 45,619.00
SKU stj29694

General Information

Product name Anti-FRK Antibody
Short Description Rabbit polyclonal to FRK
Description The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IF 1:50 - 1:200
Protein Name Anti-FRK Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human FRK (NP_002022.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 58.3 kDa
Database Links
Alternative Names FRKTyrosine-protein kinase FRK FRK antibodyPTK5 antibodyRAK
Function Non-receptor tyrosine-protein kinase that negatively regulates cell proliferation, Positively regulates PTEN protein stability through phosphorylation of PTEN on 'Tyr-336', which in turn prevents its ubiquitination and degradation, possibly by reducing its binding to NEDD4, May function as a tumor suppressor.
Cellular Localization Cytoplasm.
Tissue Specificity Predominantly expressed in epithelial derived cell lines and tissues, especially normal liver, kidney, breast and colon.
Swiss-Prot Key

 

You recently viewed

Clear recently viewed