Anti-FSCN1 Antibody

Rs. 61,689.00
SKU stj27695

General Information

Product name Anti-FSCN1 Antibody
Short Description Rabbit polyclonal to FSCN1
Description This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.
Applications WB,IHC,FC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:100
FC 1:20 - 1:50
Protein Name Anti-FSCN1 Antibody
Immunogen A synthetic peptide of human FSCN1
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 54.5 kDa
Database Links
Alternative Names FSCN1Fascin antibody55 kDa actin-bundling protein antibodySinged-like protein antibodyp55FSCN1 antibodyFAN1 antibodyHSN antibodySNL
Function Organizes filamentous actin into bundles with a minimum of 4,1:1 actin/fascin ratio, Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers, Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.
Cellular Localization Cytoplasm, cytosol.
Tissue Specificity Ubiquitous
Swiss-Prot Key

 

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