Anti-FUS Antibody

Rs. 45,619.00
SKU stj27717

General Information

Product name Anti-FUS Antibody
Short Description Rabbit polyclonal to FUS
Description This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.
Applications WB
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:100
Protein Name Anti-FUS Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 297-526 of human FUS (NP_004951.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 53.4 kDa
Database Links
Alternative Names FUSRNA-binding protein FUS antibody75 kDa DNA-pairing protein antibodyOncogene FUS antibodyOncogene TLS antibodyPOMp75 antibodyTranslocated in liposarcoma proteinFUS antibodyTLS
Function Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single-stranded DNAs and D-loop formation in superhelical double-stranded DNA, May play a role in maintenance of genomic integrity
Cellular Localization Nucleus
Tissue Specificity Ubiquitous
Swiss-Prot Key

 

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