Anti-GABARAPL2 Antibody

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Rs. 34,800.00
Rs. 32,800.00
SKU stj110092

General Information

Product name Anti-GABARAPL2 Antibody
Short Description Rabbit polyclonal to GABARAPL2
Description
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:20 - 1:50
Protein Name Gamma-aminobutyric acid receptor-associated protein-like 2GABA(Areceptor-associated protein-like 2Ganglioside expression factor 2GEF-2General protein transport factor p16Golgi-associated ATPase enhancer of 16 kDaGATE-16MAP1 light chain 3-related protein
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-117 of human GABARAPL2 (NP_009216.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 13.7 kDa
Database Links
Alternative Names GABARAPL2Gamma-aminobutyric acid receptor-associated protein-like 2 antibodyGABA(A antibodyreceptor-associated protein-like 2 antibodyGanglioside expression factor 2 antibodyGEF-2 antibodyGeneral protein transport factor p16 antibodyGolgi-associated ATPase enhancer of 16 kDa antibodyGATE-16 antibodyMAP1 light chain 3-related proteinGABARAPL2 antibodyFLC3A antibodyGEF2
Function Ubiquitin-like modifier involved in intra-Golgi traffic, Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation, It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity), Involved in autophagy, Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production, Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
Cellular Localization Golgi apparatus
Tissue Specificity Ubiquitous, expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle, expressed at very low levels in lung, thymus and small intestine.
Swiss-Prot Key

 

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