Anti-GABBR2 Antibody

Rs. 45,619.00
SKU stj28677

General Information

Product name Anti-GABBR2 Antibody
Short Description Rabbit polyclonal to GABBR2
Description The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-GABBR2 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 60-310 of human GABBR2 (NP_005449.5).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 105.8 kDa
Database Links
Alternative Names GABBR2Gamma-aminobutyric acid type B receptor subunit 2 antibodyGABA-B receptor 2 antibodyGABA-B-R2 antibodyGABA-BR2 antibodyGABABR2 antibodyGb2 antibodyG-protein coupled receptor 51 antibodyHG20GABBR2 antibodyGPR51 antibodyGPRC3B
Function Component of a heterodimeric G-protein coupled receptor for GABA, formed by GABBR1 and GABBR2.
Cellular Localization Cell membrane
Tissue Specificity Highly expressed in brain, especially in cerebral cortex, thalamus, hippocampus, frontal, occipital and temporal lobe, occipital pole and cerebellum, followed by corpus callosum, caudate nucleus, spinal cord, amygdala and medulla.
Swiss-Prot Key

 

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