Anti-GAPDH Antibody (Biotin)

Rs. 68,577.00
SKU stj73172

General Information

Product name Anti-GAPDH Antibody (Biotin)
Short Description Goat polyclonal to GAPDH (Biotin)
Description
Applications ELISA, WB, IHC
Dilution range
Protein Name Anti-GAPDH Antibody (Biotin)
Immunogen internal region
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Biotin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 36.1 kDa
Database Links
Alternative Names GAPDHGlyceraldehyde-3-phosphate dehydrogenase antibodyGAPDHGAPDH antibodyGAPD antibodyCDABP0047 antibodyOK/SW-cl.12
Function Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively, Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis, Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC, Modulates the organization and assembly of the cytoskeleton, Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity), Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate, Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes, Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation,
Cellular Localization Cytoplasm, cytosol,
Tissue Specificity
Swiss-Prot Key

 

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