Anti-GAS2 Antibody

Rs. 45,619.00
SKU stj23749

General Information

Product name Anti-GAS2 Antibody
Short Description Rabbit polyclonal to GAS2
Description The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis. It can also modulate cell susceptibility to p53-dependent apoptosis by inhibiting calpain activity. Alternative splicing results in multiple transcript variants.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Protein Name Anti-GAS2 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human GAS2 (NP_005247.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 34.9 kDa
Database Links
Alternative Names GAS2Growth arrest-specific protein 2 antibodyGAS-2GAS2
Function May play a role in apoptosis by acting as a cell death substrate for caspases, Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells, May be involved in the membrane ruffling process (By similarity).
Cellular Localization Cytoplasm, cytoskeleton.
Tissue Specificity Ubiquitously expressed with highest levels in liver, lung, and kidney, not found in spleen
Swiss-Prot Key

 

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