Anti-GATA-4 antibody

Rs. 50,211.00
SKU stj93226

General Information

Product name Anti-GATA-4 antibody
Short Description
Description Rabbit polyclonal to GATA-4.
Applications WB,IHC,IF,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000
Protein Name Anti-GATA-4 antibody
Immunogen Synthesized peptide derived from human GATA-4 around the non-phosphorylation site of S105.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 48 kDa
Database Links
Alternative Names Transcription factor GATA-4 antibody
GATA-binding factor 4 antibody
Function Transcriptional activator that binds to the consensus sequence 5'-AGATAG-3' and plays a key role in cardiac development and function . In cooperation with TBX5, it binds to cardiac super-enhancers and promotes cardiomyocyte gene expression, while it downregulates endocardial and endothelial gene expression . Involved in bone morphogenetic protein (BMP)-mediated induction of cardiac-specific gene expression. Binds to BMP response element (BMPRE) DNA sequences within cardiac activating regions . Acts as a transcriptional activator of ANF in cooperation with NKX2-5 . Promotes cardiac myocyte enlargement . Required during testicular development . May play a role in sphingolipid signaling by regulating the expression of sphingosine-1-phosphate degrading enzyme, spingosine-1-phosphate lyase .
Cellular Localization Nucleus
Tissue Specificity
Swiss-Prot Key

 

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