Anti-GATM Antibody

Rs. 45,619.00
SKU stj28681

General Information

Product name Anti-GATM Antibody
Short Description Rabbit polyclonal to GATM
Description This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
Protein Name Anti-GATM Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 124-423 of human GATM (NP_001473.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


Gene ID
Gene Symbol
Molecular Weight 48.5 kDa
Database Links
Alternative Names GATMGlycine amidinotransferase antibodymitochondrial GATM antibodyAGAT
Function Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine, Creatine plays a vital role in energy metabolism in muscle tissues, May play a role in embryonic and central nervous system development, May be involved in the response to heart failure by elevating local creatine synthesis.
Cellular Localization Mitochondrion inner membrane
Tissue Specificity Expressed in brain, heart, kidney, liver, lung, salivary gland and skeletal muscle tissue, with the highest expression in kidney, biallelically expressed in placenta and fetal tissues.
Swiss-Prot Key


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