Anti-GCSH Antibody

Rs. 61,689.00
SKU stj26502

General Information

Product name Anti-GCSH Antibody
Short Description Rabbit polyclonal to GCSH
Description Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). The protein encoded by this gene is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in this gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for this gene. Also, several transcribed and non-transcribed pseudogenes of this gene exist throughout the genome.
Applications WB
Dilution range WB 1:500 - 1:1000
Protein Name Anti-GCSH Antibody
Immunogen A synthetic peptide of human GCSH
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 18.9 kDa
Database Links
Alternative Names GCSHGlycine cleavage system H protein antibodymitochondrial antibodyLipoic acid-containing proteinGCSH
Function The glycine cleavage system catalyzes the degradation of glycine, The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST).
Cellular Localization Mitochondrion
Tissue Specificity
Swiss-Prot Key

 

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