Anti-GDI1 Antibody

Rs. 45,619.00
SKU stj27415

General Information

Product name Anti-GDI1 Antibody
Short Description Rabbit polyclonal to GDI1
Description GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI1 is expressed primarily in neural and sensory tissues. Mutations in GDI1 have been linked to X-linked nonspecific mental retardation.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-GDI1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 188-447 of human GDI1 (NP_001484.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 50.6 kDa
Database Links
Alternative Names GDI1Rab GDP dissociation inhibitor alpha antibodyRab GDI alpha antibodyGuanosine diphosphate dissociation inhibitor 1 antibodyGDI-1 antibodyOligophrenin-2 antibodyProtein XAP-4GDI1 antibodyGDIL antibodyOPHN2 antibodyRABGDIA antibodyXAP4
Function Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them, Promotes the dissociation of GDP-bound Rab proteins from the membrane and inhibits their activation, Promotes the dissociation of RAB1A, RAB3A, RAB5A and RAB10 from membranes.
Cellular Localization Cytoplasm
Tissue Specificity Brain
Swiss-Prot Key

 

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