Anti-GluR-2 antibody

Rs. 50,211.00
SKU stj93288

General Information

Product name Anti-GluR-2 antibody
Short Description
Description Rabbit polyclonal to GluR-2.
Applications WB,IHC,IF,ELISA
Dilution range WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000
Protein Name Anti-GluR-2 antibody
Immunogen Synthesized peptide derived from human GluR-2 around the non-phosphorylation site of S880.
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity Human,Mouse,Rat
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 99 kDa
Database Links
Alternative Names Glutamate receptor 2 antibody
AMPA-selective glutamate receptor 2 antibody
GluR-B antibody
GluR-K2 antibody
Glutamate receptor ionotropic, AMPA 2 antibody
GluA2 antibody
GLUR2 antibody
Function Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Cellular Localization Cell membrane Endoplasmic reticulum membrane Cell junction, synapse, postsynaptic cell membrane. Interaction with CACNG2, CNIH2 and CNIH3 promotes cell surface expression.
Tissue Specificity
Swiss-Prot Key

 

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