Anti-GNAI3 Antibody

Rs. 45,619.00
SKU stj29871

General Information

Product name Anti-GNAI3 Antibody
Short Description Rabbit polyclonal to GNAI3
Description Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway.
Applications WB,IHC
Dilution range WB 1:1000 - 1:2000
IHC 1:50 - 1:100
Protein Name Anti-GNAI3 Antibody
Immunogen A synthetic peptide corresponding to a sequence within amino acids 1-100 of human GNAI3 (NP_006487.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 40.5 kDa
Database Links
Alternative Names GNAI3Guanine nucleotide-binding protein G(k antibodysubunit alpha antibodyG(i antibodyalpha-3GNAI3
Function Heterotrimeric guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs) in numerous signaling cascades, The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state, Signaling by an activated GPCR promotes GDP release and GTP binding, The alpha subunit has a low GTPase activity that converts bound GTP to GDP, thereby terminating the signal, Both GDP release and GTP hydrolysis are modulated by numerous regulatory proteins.
Cellular Localization Cytoplasm
Tissue Specificity
Swiss-Prot Key

 

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