Anti-GOT1 Antibody

Rs. 45,619.00
SKU stj28385

General Information

Product name Anti-GOT1 Antibody
Short Description Rabbit polyclonal to GOT1
Description Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.
Applications WB,IHC,IF
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:10 - 1:100
Protein Name Anti-GOT1 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 244-413 of human GOT1 (NP_002070.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 46.2 kDa
Database Links
Alternative Names GOT1Aspartate aminotransferase antibodycytoplasmic antibodycAspATGOT1
Function Biosynthesis of L-glutamate from L-aspartate or L-cysteine, Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system, Acts as a scavenger of glutamate in brain neuroprotection, The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis, Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide, Mercaptopyruvate is converted into H(2)S via the action of 3-mercaptopyruvate sulfurtransferase (3MST), Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.
Cellular Localization Cytoplasm
Tissue Specificity
Swiss-Prot Key

 

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