Anti-GP9 Antibody

Rs. 45,619.00
SKU stj27327

General Information

Product name Anti-GP9 Antibody
Short Description Rabbit polyclonal to GP9
Description This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency.
Applications WB,IF
Dilution range WB 1:500 - 1:2000
IHC 1:20 - 1:100
IF 1:20 - 1:100
Protein Name Anti-GP9 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 17-147 of human GP9 (NP_000165.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 19 kDa
Database Links
Alternative Names GP9Platelet glycoprotein IX antibodyGP-IX antibodyGPIX antibodyGlycoprotein 9 antibodyCD antigen CD42aGP9
Function The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels, The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis, GP-IX may provide for membrane insertion and orientation of GP-Ib
Cellular Localization Membrane
Tissue Specificity
Swiss-Prot Key

 

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