Anti-GPR68 Antibody

Rs. 45,619.00
SKU stj29487

General Information

Product name Anti-GPR68 Antibody
Short Description Rabbit polyclonal to GPR68
Description The protein encoded by this gene is a G protein-coupled receptor for sphingosylphosphorylcholine. The encoded protein is a proton-sensing receptor, inactive at pH 7.8 but active at pH 6.8. Mutations in this gene are a cause of amelogenesis imperfecta.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-GPR68 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 276-365 of human GPR68 (NP_003476.3).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 41.1 kDa
Database Links
Alternative Names GPR68Ovarian cancer G-protein coupled receptor 1 antibodyOGR-1 antibodyG-protein coupled receptor 68 antibodyGPR12A antibodySphingosylphosphorylcholine receptorGPR68 antibodyOGR1
Function Proton-sensing receptor involved in pH homeostasis, May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone, Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization, The receptor is almost silent at pH 7,8 but fully activated at pH 6,8, Function also as a metastasis suppressor gene in prostate cancer (By similarity).
Cellular Localization Cell membrane
Tissue Specificity Found at low level in a wide range of tissues, but significantly expressed in lung, kidney, bone and nervous system.
Swiss-Prot Key

 

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