Anti-GPRC6A antibody

Rs. 50,211.00
SKU stj93405

General Information

Product name Anti-GPRC6A antibody
Short Description
Description Rabbit polyclonal to GPRC6A.
Applications WB,IF,ELISA
Dilution range WB 1:500-1:2000IF 1:200-1:1000ELISA 1:5000
Protein Name Anti-GPRC6A antibody
Immunogen Synthesized peptide derived from human GPRC6A
Storage Instruction Store at -20°C, and avoid repeat freeze-thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Target

Gene ID
Gene Symbol
Molecular Weight 105 kDa
Database Links
Alternative Names G-protein coupled receptor family C group 6 member A antibody
hGPRC6A antibody
G-protein coupled receptor GPCR33 antibody
hGPCR33 antibody
Function Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca(2+) and Mg(2+). Activated by extracellular calcium and osteocalcin. Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Mediates the non-genomic effects of androgens in multiple tissue. May coordinate nutritional and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalent ions and its responsiveness to anabolic steroids.
Cellular Localization Cell membrane
Tissue Specificity Isoform 1 is expressed at high level in brain, skeletal muscle, testis, bone, calvaria, osteoblasts and leukocytes. Expressed at intermediate level in liver, heart, kidney and spleen. Expressed at low level in lung, pancreas, placenta and ovary. Not detected in thymus, prostate, small intestine, tongue and colon. Isoform 1 and isoform 2 are expressed in kidney at the same level. Isoform 2 is expressed at lower level than isoform 1 in the other tissues.
Swiss-Prot Key

 

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