Anti-GPS1 Antibody

Rs. 68,577.00
SKU stj70366

General Information

Product name Anti-GPS1 Antibody
Short Description Goat polyclonal to GPS1
Description
Applications ELISA, WB
Dilution range
Protein Name Anti-GPS1 Antibody
Immunogen C Terminus
Storage Instruction
Type of Usage For Research Use Only (RUO).

Product Properties

Host Goat
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Isotype
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Target

Gene ID
Gene Symbol
Molecular Weight 55.5 kDa
Database Links
Alternative Names GPS1COP9 signalosome complex subunit 1 antibodySGN1 antibodySignalosome subunit 1 antibodyG protein pathway suppressor 1 antibodyGPS-1 antibodyJAB1-containing signalosome subunit 1 antibodyProtein MFHGPS1 antibodyCOPS1 antibodyCSN1
Function Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes, The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2, The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases, CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively, Suppresses G-protein- and mitogen-activated protein kinase-mediated signal transduction,
Cellular Localization Cytoplasm
Tissue Specificity Widely expressed,
Swiss-Prot Key

 

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