Anti-GRPR Antibody

Rs. 45,619.00
SKU stj23875

General Information

Product name Anti-GRPR Antibody
Short Description Rabbit polyclonal to GRPR
Description Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.
Applications WB
Dilution range WB 1:500 - 1:2000
Protein Name Anti-GRPR Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 235-384 of human GRPR (NP_005305.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 43.2 kDa
Database Links
Alternative Names GRPRGastrin-releasing peptide receptor antibodyGRP-R antibodyGRP-preferring bombesin receptorGRPR
Function Receptor for gastrin-releasing peptide (GRP).
Cellular Localization Cell membrane
Tissue Specificity Highly expressed in pancreas, also expressed in stomach, adrenal cortex and brain.
Swiss-Prot Key

 

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