Anti-DFNA5 Antibody

Rs. 45,619.00
SKU stj29568

General Information

Product name Anti-DFNA5 Antibody
Short Description Rabbit polyclonal to GSDME
Description Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene.
Applications WB,IHC
Dilution range WB 1:500 - 1:2000
IHC 1:50 - 1:200
Protein Name Anti-DFNA5 Antibody
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DFNA5 (NP_004394.1).
Storage Instruction Store at -20℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.


Gene ID
Gene Symbol
Molecular Weight 54.6 kDa
Database Links
Alternative Names GSDMEGasdermin-E antibodyInversely correlated with estrogen receptor expression 1 antibodyICERE-1 antibodyNon-syndromic hearing impairment protein 5GSDME antibodyDFNA5 antibodyICERE1
Function Plays a role in the TP53-regulated cellular response to DNA damage probably by cooperating with TP53.
Cellular Localization Gasdermin-E, N-terminal: Cell membrane
Tissue Specificity Expressed in cochlea, low level of expression in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas, with highest expression in placenta
Swiss-Prot Key


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