Anti-GSPT2 Antibody

Rs. 61,689.00
SKU stj26738

General Information

Product name Anti-GSPT2 Antibody
Short Description Rabbit polyclonal to GSPT2
Description This gene encodes a GTPase that belongs to the GTP-binding elongation factor family. The encoded protein is a polypeptide release factor that complexes with eukaryotic peptide chain release factor 1 to mediate translation termination. This protein may also be involved in mRNA stability.
Applications WB
Dilution range WB 1:500 - 1:1000
Protein Name Anti-GSPT2 Antibody
Immunogen A synthetic Peptide of human GSPT2
Storage Instruction Store at 4℃. Avoid freeze / thaw cycles.
Type of Usage For Research Use Only (RUO).

Product Properties

Host Rabbit
Clonality Polyclonal
Reactivity
Conjugation Unconjugated
Purification Affinity purification
Isotype IgG
Formulation Buffer: PBS with 0.02% sodium azide, pH7.3.

Target

Gene ID
Gene Symbol
Molecular Weight 68.9 kDa
Database Links
Alternative Names GSPT2Eukaryotic peptide chain release factor GTP-binding subunit ERF3B antibodyEukaryotic peptide chain release factor subunit 3b antibodyeRF3b antibodyG1 to S phase transition protein 2 homologGSPT2 antibodyERF3B
Function Involved in translation termination in response to the termination codons UAA, UAG and UGA, May play a role as a potent stimulator of the release factor activity of ETF1, Exhibits GTPase activity, which is ribosome- and ETF1-dependent, May play a role in cell cycle progression, Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
Cellular Localization Cytoplasm
Tissue Specificity Highly expressed in iucc stage ii colorectal cancer (crc).
Swiss-Prot Key

 

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